Endocrine Abstracts

Presented case demonstrates a rare diencephalic pathology — adipsic diabetes insipidus (ADI) with severe hypernatremia in a 58-year-old woman after ttranssphenoidal removal of stalk intraventricular craniopharyngioma. ADI was diagnosed because of hypernatremia (150–155 mmol/l), polyuria (up to 4 liters per day) and absence of thirst. Normalization of wa- ter-electrolyte balance occurred on the background of desmopressin therapy and sufficient hydration in postoperati...

Suprasellar craniopharyngiomas (CF) are characterised by a high incidence of involvement of the third ventricle, which determines the risk of hypothalamic obesity (HO). There are no unified diagnostic criteria for HO and its effective treatment. The assessment of pre- and postoperative hypothalamic damage is necessary for the choice of surgical strategy and early therapeutic intervention.Objective: To estimate the incidence and extent of weight gain in a...

The tumors of the thalamic-hypothalamic-pituitary system (diencephalon region, DR) include a fairly large group. These are pituitary adenomas, craniopharyngiomas (CP), pineal tumors, gliomas, meningiomas, and others. Tumors differ in the location, histological structure, and manifestations of the clinical picture with the corresponding hormonal changes, approaches and methods in treatment. Psychopathological symptoms are revealed in the symptoms of lesion of the DR in addition...